PUBLICATION

2024
  • Iwasaki T, Watanabe R, Ito H, Fujii T, Ohmura K, Yoshitomi H, Murata K, Murakami K, Onishi A, Tanaka M, Matsuda S, Matsuda F, Morinobu A, Hashimoto M. Monocyte-derived transcriptomes explain the ineffectiveness of abatacept in rheumatoid arthritis. Arthritis Res Ther. 2023 PMID: 38167328 PMCID: PMC10759752
2023
  • Yoshitomi H. Peripheral helper T cells, mavericks of peripheral immune responses. International immunology 2023 PMID: 37788648 PMCID: PMC10823579
  • Yoshida S, Nishitani K, Yoshitomi H, Kuriyama S, Nakamura S, Fujii T, Saito M, Kobori Y, Murakami A, Murata K, Ito H, Ueno H, Matsuda S. Knee alignment correction by high tibial osteotomy reduces symptoms and synovial inflammation in knee osteoarthritis accompanied by macrophage phenotypic change from M1 to M2. Arthritis Rheumatol. 2023 PMID: 36530127
  • Umemoto A, Kuwada T, Murata K, Shiokawa M, Ota S, Murotani Y, Itamoto A, Nishitani K, Yoshitomi H, Fujii T, Onishi A, Onizawa H, Murakami K, Tanaka M, Ito H, Seno H, Morinobu A, Matsuda S. Identification of anti-citrullinated osteopontin antibodies and increased inflammatory response by enhancement of osteopontin binding to fibroblast-like synoviocytes in rheumatoid arthritis. Arthritis Res Ther. 2023 PMID: 36804906 PMCID: PMC9936655
  • Umemoto A, Ito H, Azukizawa M, Murata K, Tanaka M, Fujii T, Onishi A, Onizawa H, Ishie S, Murakami A, Nishitani K, Murakami K, Yoshitomi H, Hashimoto M, Morinobu A, Matsuda S. How do symptoms of each joint contribute to global pain, disease activity and functional disability in rheumatoid arthritis?-A comprehensive association study using a large cohort. PLoS One. 2023 PMID: 37624815 PMCID: PMC10456163
  • Moriya K, Nakano T, Honda Y, Tsumura M, Ogishi M, Sonoda M, Nishitani-Isa M, Uchida T, Hbibi M, Mizoguchi Y, Ishimura M, Izawa K, Asano T, Kakuta F, Abukawa D, Rinchai D, Zhang P, Kambe N, Bousfiha A, Yasumi T, Boisson B, Puel A, Casanova JL, Nishikomori R, Ohga S, Okada S, Sasahara Y, Kure S. Human RELA dominant-negative mutations underlie type I interferonopathy with autoinflammation and autoimmunity. J Exp Med. 2023 PMID: 37273177 PMCID: PMC10242411
  • Miyamoto T, Izawa K, Masui S, Yamazaki A, Yamasaki Y, Matsubayashi T, Shiraki M, Ohnishi H, Yasumura J, Kawabe T, Miyamae T, Matsubara T, Arakawa N, Ishige T, Takizawa T, Shimbo A, Shimizu M, Kimura N, Maeda Y, Maruyama Y, Shigemura T, Furuta J, Sato S, Tanaka H, Izumikawa M, Yamamura M, Hasegawa T, Kaneko H, Nakagishi Y, Nakano N, Iida Y, Nakamura T, Wakiguchi H, Hoshina T, Kawai T, Murakami K, Akizuki S, Morinobu A, Ohmura K, Eguchi K, Sonoda M, Ishimura M, Furuno K, Kashiwado M, Mori M, Kawahata K, Hayama K, Shimoyama K, Sasaki N, Ito T, Umebayashi H, Omori T, Nakamichi S, Dohmoto T, Hasegawa Y, Kawashima H, Watanabe S, Taguchi Y, Nakaseko H, Iwata N, Kohno H, Ando T, Ito Y, Kataoka Y, Saeki T, Kaneko U, Murase A, Hattori S, Nozawa T, Nishimura K, Nakano R, Watanabe M, Yashiro M, Nakamura T, Komai T, Kato K, Honda Y, Hiejima E, Yonezawa A, Bessho K, Okada S, Ohara O, Takita J, Yasumi T, Nishikomori R. Characteristics of Cryopyrin-Associated Periodic Syndrome and Long-Term Real-World Efficacy and Tolerability of Canakinumab in Japan: Results of a Nationwide Survey. ; Japan CAPS Working Group. Arthritis Rheumatol. 2023 PMID: 38268504
  • Kimura K, Nishigori R, Hamatani M, Sawamura M, Ashida S, Fujii C, Takata M, Lin Y, Sato W, Okamoto T, Kuzuya A, Takahashi R, Yamamura T, Kondo T. Resident memory-like CD8+ T cells are involved in chronic inflammatory and neurodegenerative diseases in the central nervous system. Neurol Neuroimmunol Neuroinflamm. 2023 PMID: 37949669 PMCID: PMC10691221
  • Hamatani M, Kondo T. Immunological role of sulfatide in the pathogenesis of multiple sclerosis. Neural Regen Res. 2023 PMID: 36926716 PMCID: PMC10233772
  • 吉富啓之上野英樹 ポストGWAS時代の遺伝統計学 : オミクス解析と機械学習でヒト疾患を俯瞰する. シングルセル解析によるヒト疾患病態解明 2023
2022
  • Yasutomi, M., A.F. Christiaansen, N. Imai, N. Martin-Orozco, C.V. Forst, G. Chen, and H. Ueno. CD226 and TIGIT Cooperate in the Differentiation and Maturation of Human Tfh Cells. Front Immunol. 2022;13:840457. PubMed PMID: 35273617; PMCID: PMC8902812.
  • Ukita, M., J. Hamanishi, H. Yoshitomi, K. Yamanoi, S. Takamatsu, A. Ueda, H. Suzuki, Y. Hosoe, Y. Furutake, M. Taki, K. Abiko, K. Yamaguchi, H. Nakai, T. Baba, N. Matsumura, A. Yoshizawa, H. Ueno, and M. Mandai. CXCL13-producing CD4+ T cells accumulate in early phase of tertiary lymphoid structures in ovarian cancer. JCI Insight. 2022. PubMed PMID: 35552285.
  • Tanaka, T., T. Shiba, Y. Honda, K. Izawa, T. Yasumi, M.K. Saito, and R. Nishikomori. Induced Pluripotent Stem Cell-Derived Monocytes/Macrophages in Autoinflammatory Diseases. Front Immunol. 2022;13:870535. PubMed PMID: 35603217; PMCID: PMC9120581.
  • Nishitani-Isa, M., K. Mukai, Y. Honda, H. Nihira, T. Tanaka, H. Shibata, K. Kodama, E. Hiejima, K. Izawa, Y. Kawasaki, M. Osawa, Y. Katata, S. Onodera, T. Watanabe, T. Uchida, S. Kure, J. Takita, O. Ohara, M.K. Saito, R. Nishikomori, T. Taguchi, Y. Sasahara, and T. Yasumi. Trapping of CDC42 C-terminal variants in the Golgi drives pyrin inflammasome hyperactivation. J Exp Med. 2022;219(6). PubMed PMID: 35482294; PMCID: PMC9059393.
  • Nakajima, K., E. Hiejima, H. Nihira, K. Kato, Y. Honda, K. Izawa, N. Kawabata, I. Kato, E. Ogawa, M. Sonoda, T. Okamoto, H. Okajima, T. Yasumi, and J. Takita. Case Report: A Case of Epstein-Barr Virus-Associated Acute Liver Failure Requiring Hematopoietic Cell Transplantation After Emergent Liver Transplantation. Front Immunol. 2022;13:825806. PubMed PMID: 35154146; PMCID: PMC8834065.
  • Murata, K., S. Ito, A. Suzuki, C. Terao, S. Ishie, A. Umemoto, Y. Murotani, K. Nishitani, H. Yoshitomi, and T. Fujii. LSD1 metabolically integrates osteoclast differentiation and inflammatory bone resorption through HIF-1α and E2F1. Arthritis & Rheumatology (Hoboken, NJ). 2022.
  • Matsubayashi, T., M. Yamamoto, S. Takayama, Y. Otsuki, I. Yamadori, Y. Honda, K. Izawa, R. Nishikomori, and T. Oto. Allograft Dysfunction After Lung Transplantation for COPA Syndrome: A Case Report and Literature Review. Mod Rheumatol Case Rep. 2022. PubMed PMID: 35079820.
  • Iwamoto, Y., and H. Ueno. Circulating T Follicular Helper Subsets in Human Blood. Methods Mol Biol. 2022;2380:29-39. PubMed PMID: 34802119.
  • Inoue, Y., T. Yamamoto, Y. Honda, K. Izawa, and T. Yasumi. 2022. Partial Trisomy 9p with Clinical Symptoms Resembling Interferonopathies. In J Clin Immunol. Netherlands. 203-205.
  • Higuchi, T., K. Izawa, T. Miyamoto, Y. Honda, A. Nishiyama, M. Shimizu, J. Takita, and T. Yasumi. An efficient diagnosis: A patient with X-linked inhibitor of apoptosis protein (XIAP) deficiency in the setting of infantile hemophagocytic lymphohistiocytosis was diagnosed using high serum interleukin-18 combined with common laboratory parameters. Pediatr Blood Cancer. 2022:e29606. PubMed PMID: 35187790.
  • Hamatani, M., H. Ochi, K. Kimura, S. Ashida, Y. Hashi, Y. Okada, C. Fujii, K. Kawamura, T. Mizuno, H. Ueno, R. Takahashi, and T. Kondo. T cells from MS Patients with High Disease Severity Are Insensitive to an Immune-Suppressive Effect of Sulfatide. Molecular neurobiology. 2022. PubMed PMID: 35689766.
  • Doi, K., K. Murata, S. Ito, A. Suzuki, C. Terao, S. Ishie, A. Umemoto, Y. Murotani, K. Nishitani, and H. Yoshitomi. Role of Lysine‐Specific Demethylase 1 in Metabolically Integrating Osteoclast Differentiation and Inflammatory Bone Resorption Through Hypoxia‐Inducible Factor 1α and E2F1. Arthritis & Rheumatology. 2022.
2021
  • Zhang, B., A. Vogelzang, M. Miyajima, Y. Sugiura, Y. Wu, K. Chamoto, R. Nakano, R. Hatae, R.J. Menzies, K. Sonomura, N. Hojo, T. Ogawa, W. Kobayashi, Y. Tsutsui, S. Yamamoto, M. Maruya, S. Narushima, K. Suzuki, H. Sugiya, K. Murakami, M. Hashimoto, H. Ueno, T. Kobayashi, K. Ito, T. Hirano, K. Shiroguchi, F. Matsuda, M. Suematsu, T. Honjo, and S. Fagarasan. B cell-derived GABA elicits IL-10(+) macrophages to limit anti-tumour immunity. Nature. 2021;599(7885):471-476. PubMed PMID: 34732892; PMCID: PMC8599023.
  • Yoshitomi, H., and H. Ueno. Shared and distinct roles of T peripheral helper and T follicular helper cells in human diseases. Cell Mol Immunol. 2021;18(3):523-527. PubMed PMID: 32868910; PMCID: 8027819.
  • Yokoi, K., S. Minamiguchi, Y. Honda, M. Kobayashi, S. Kobayashi, and R. Nishikomori. Necrotizing Funisitis as an Intrauterine manifestation of Cryopyrin-Associated Periodic Syndrome: a case report and review of the literature. Pediatr Rheumatol Online J. 2021;19(1):77. PubMed PMID: 34059097; PMCID: PMC8165790.
  • Yamashita, A., H. Yoshitomi, S. Kihara, J. Toguchida, and N. Tsumaki. Culture substrate-associated YAP inactivation underlies chondrogenic differentiation of human induced pluripotent stem cells. Stem Cells Transl Med. 2021;10(1):115-127. PubMed PMID: 32822104; PMCID: 7780802.
  • Yamada, D., M. Nakamura, T. Takao, S. Takihira, A. Yoshida, S. Kawai, A. Miura, L. Ming, H. Yoshitomi, M. Gozu, K. Okamoto, H. Hojo, N. Kusaka, R. Iwai, E. Nakata, T. Ozaki, J. Toguchida, and T. Takarada. Induction and expansion of human PRRX1(+) limb-bud-like mesenchymal cells from pluripotent stem cells. Nat Biomed Eng. 2021;5(8):926-940. PubMed PMID: 34373601.
  • Wu, J., H. Cheng, H. Wang, G. Zang, L. Qi, X. Lv, C. Liu, S. Zhu, M. Zhang, J. Cui, H. Ueno, Y.J. Liu, J. Suo, and J. Chen. Correlation Between Immune Lymphoid Cells and Plasmacytoid Dendritic Cells in Human Colon Cancer. Front Immunol. 2021;12:601611. PubMed PMID: 33708200; PMCID: PMC7940519.
  • Tomizawa, T., K. Nishitani, H. Ito, Y. Okae, Y. Morita, K. Doi, M. Saito, S. Ishie, S. Yoshida, K. Murata, H. Yoshitomi, Y. Kuroda, and S. Matsuda. The limitations of mono- and combination antibiotic therapies on immature biofilms in a murine model of implant-associated osteomyelitis. J Orthop Res. 2021;39(2):449-457. PubMed PMID: 33325059.
  • Shiraki, M., E. Williams, N. Yokoyama, K. Shinoda, Z. Nademi, K. Matsumoto, H. Nihira, Y. Honda, K. Izawa, R. Nishikomori, M.A. Slatter, A.J. Cant, A.R. Gennery, H. Ohnishi, and H. Kanegane. 2021. Hematopoietic Cell Transplantation Ameliorates Autoinflammation in A20 Haploinsufficiency. In J Clin Immunol. Netherlands. 1954-1956.
  • Shimizu, M., T. Matsubayashi, H. Ohnishi, M. Nakama, K. Izawa, Y. Honda, and R. Nishikomori. Haploinsufficiency of A20 with a novel mutation of deletion of exons 2-3 of TNFAIP3. Mod Rheumatol. 2021a;31(2):493-497. PubMed PMID: 32011208.
  • Shimizu, M., N. Inoue, M. Mizuta, H. Irabu, M. Okajima, Y. Honda, H. Nihira, K. Izawa, A. Yachie, and T. Wada. Successful treatment of spondyloenchondrodysplasia with baricitinib. Rheumatology (Oxford). 2021b;60(2):e44-e46. PubMed PMID: 32856090.
  • Saito, M., K. Nishitani, H.O. Ikeda, S. Yoshida, S. Iwai, X. Ji, A. Nakahata, A. Ito, S. Nakamura, S. Kuriyama, H. Yoshitomi, K. Murata, T. Aoyama, H. Ito, H. Kuroki, A. Kakizuka, and S. Matsuda. A VCP modulator, KUS121, as a promising therapeutic agent for post-traumatic osteoarthritis (vol 10, 20787, 2020). Scientific Reports. 2021;11(1). PubMed PMID: WOS:000636356000001.
  • Okazaki, F., H. Wakiguchi, Y. Korenaga, T. Nakamura, H. Yasudo, S. Uchi, R. Yanai, N. Asano, Y. Hoshii, T. Tanabe, K. Izawa, Y. Honda, R. Nishikomori, K. Uchida, Y. Eishi, S. Ohga, and S. Hasegawa. A novel mutation in early-onset sarcoidosis/Blau syndrome: an association with Propionibacterium acnes. Pediatr Rheumatol Online J. 2021;19(1):18. PubMed PMID: 33602264; PMCID: PMC7890802.
  • Nihira, H., K. Izawa, M. Ito, H. Umebayashi, T. Okano, S. Kajikawa, E. Nanishi, D. Keino, K. Murakami, M. Isa-Nishitani, T. Shiba, Y. Honda, A. Hijikata, T. Yasu, T. Kubota, Y. Hasegawa, Y. Kawashima, N. Nakano, H. Takada, S. Ohga, T. Heike, J. Takita, O. Ohara, S. Takei, M. Takahashi, H. Kanegane, T. Morio, S. Iwaki-Egawa, Y. Sasahara, R. Nishikomori, and T. Yasumi. Detailed analysis of Japanese patients with adenosine deaminase 2 deficiency reveals characteristic elevation of type II interferon signature and STAT1 hyperactivation. J Allergy Clin Immunol.2021;148(2):550-562. PubMed PMID: 33529688.
  • Kato, T., M. Yamamoto, Y. Honda, T. Orimo, I. Sasaki, K. Murakami, H. Hemmi, Y. Fukuda-Ohta, K. Isono, S. Takayama, H. Nakamura, Y. Otsuki, T. Miyamoto, J. Takita, T. Yasumi, R. Nishikomori, T. Matsubayashi, K. Izawa, and T. Kaisho. Augmentation of Stimulator of Interferon Genes-Induced Type I Interferon Production in COPA Syndrome. Arthritis Rheumatol. 2021;73(11):2105-2115. PubMed PMID: 33982886.
  • Kanazawa, N., H. Hemmi, N. Kinjo, H. Ohnishi, J. Hamazaki, H. Mishima, A. Kinoshita, T. Mizushima, S. Hamada, K. Hamada, N. Kawamoto, S. Kadowaki, Y. Honda, K. Izawa, R. Nishikomori, M. Tsumura, Y. Yamashita, S. Tamura, T. Orimo, T. Ozasa, T. Kato, I. Sasaki, Y. Fukuda-Ohta, N. Wakaki-Nishiyama, Y. Inaba, K. Kunimoto, S. Okada, T. Taketani, K. Nakanishi, S. Murata, K.I. Yoshiura, and T. Kaisho. Heterozygous missense variant of the proteasome subunit β-type 9 causes neonatal-onset autoinflammation and immunodeficiency. Nat Commun. 2021;12(1):6819. PubMed PMID: 34819510; PMCID: PMC8613290.
  • Jo, N., R. Zhang, H. Ueno, T. Yamamoto, D. Weiskopf, M. Nagao, S. Yamanaka, and Y. Hamazaki. Aging and CMV Infection Affect Pre-existing SARS-CoV-2-Reactive CD8+ T Cells in Unexposed Individuals. Frontiers Aging. 2021;2:719342.
  • Horiuchi, S., H. Wu, W.C. Liu, N. Schmitt, J. Provot, Y. Liu, S.E. Bentebibel, R.A. Albrecht, M. Schotsaert, C.V. Forst, B. Zhang, and H. Ueno. Tox2 is required for the maintenance of GC TFH cells and the generation of memory TFH cells. Sci Adv. 2021;7(41):eabj1249. PubMed PMID: 34623911; PMCID: PMC8500513.
  • Honda, Y., Y. Maeda, K. Izawa, T. Shiba, T. Tanaka, H. Nakaseko, K. Nishimura, H. Mukoyama, M. Isa-Nishitani, T. Miyamoto, H. Nihira, H. Shibata, E. Hiejima, O. Ohara, J. Takita, T. Yasumi, and R. Nishikomori. Rapid Flow Cytometry-Based Assay for the Functional Classification of MEFV Variants. J Clin Immunol. 2021;41(6):1187-1197. PubMed PMID: 33733382.
  • Ashida, S., H. Ochi, M. Hamatani, C. Fujii, R. Nishigori, K. Kawamura, S. Matsumoto, M. Nakagawa, R. Takahashi, T. Mizuno, and T. Kondo. Radiological and Laboratory Features of Multiple Sclerosis Patients With Immunosuppressive Therapy: A Multicenter Retrospective Study in Japan. Frontiers in neurology. 2021a;12:749406. PubMed PMID: 34721276; PMCID: PMC8548818.
  • Ashida, S., H. Ochi, M. Hamatani, C. Fujii, K. Kimura, Y. Okada, Y. Hashi, K. Kawamura, H. Ueno, R. Takahashi, T. Mizuno, and T. Kondo. Immune Skew of Circulating Follicular Helper T Cells Associates With Myasthenia Gravis Severity. Neurol Neuroimmunol Neuroinflamm. 2021b;8(2). PubMed PMID: 33436376.
2020
  • Yoshitomi, H. CXCL13-producing PD-1(hi)CXCR5(-) helper T cells in chronic inflammation. Immunol Med. 2020;43(4):156-160. PubMed PMID: 32584200.
  • Ueno, H. The IL-12-STAT4 axis in the pathogenesis of human systemic lupus erythematosus. Eur J Immunol. 2020;50(1):10-16. PubMed PMID: 31762023.
  • Scholze, H., R.E. Stephenson, R. Reynolds, S. Shah, R. Puri, S.D. Butler, V. Trujillo-Alonso, M.R. Teater, H.v. Besien, D. Gibbs-Curtis, H. Ueno, S. Parvin, A. Letai, S. Mathew, A. Singh, E. Cesarman, A. Melnick, and L. Giulino-Roth. Combined EZH2 and Bcl-2 inhibitors as precision therapy for genetically defined DLBCL subtypes. Blood Advances. 2020;4(20):5226-5231.
  • Saito, M., K. Nishitani, H.O. Ikeda, S. Yoshida, S. Iwai, X. Ji, A. Nakahata, A. Ito, S. Nakamura, S. Kuriyama, H. Yoshitomi, K. Murata, T. Aoyama, H. Ito, H. Kuroki, A. Kakizuka, and S. Matsuda. A VCP modulator, KUS121, as a promising therapeutic agent for post-traumatic osteoarthritis. Scientific Reports. 2020;10(1):1-12. PubMed PMID: WOS:000596311200019.
  • Okahata, A., H. Ito, M. Furu, M. Ishikawa, T. Fujii, M. Hashimoto, M. Tanaka, Y. Morita, M. Azukizawa, T. Tomizawa, K. Doi, K. Nishitani, K. Murata, H. Yoshitomi, T. Mimori, and S. Matsuda. Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor 1 Predicts the Changes of Rheumatoid Factor Titers in Rheumatoid Arthritis. J Clin Rheumatol. 2020;26(7):295-300. PubMed PMID: 31397763.
  • Matsuda, T., N. Kambe, Y. Ueki, N. Kanazawa, K. Izawa, Y. Honda, A. Kawakami, S. Takei, K. Tonomura, M. Inoue, H. Kobayashi, I. Okafuji, Y. Sakurai, N. Kato, Y. Maruyama, Y. Inoue, Y. Otsubo, T. Makino, S. Okada, I. Kobayashi, M. Yashiro, S. Ito, H. Fujii, Y. Kondo, N. Okamoto, N. Iwata, U. Kaneko, M. Doi, J. Hosokawa, O. Ohara, M.K. Saito, and R. Nishikomori. Clinical characteristics and treatment of 50 cases of Blau syndrome in Japan confirmed by genetic analysis of the NOD2 mutation. Ann Rheum Dis. 2020a;79(11):1492-1499. PubMed PMID: 32647028.
  • Matsuda, M., Y. Yamanaka, M. Uemura, M. Osawa, M.K. Saito, A. Nagahashi, M. Nishio, L. Guo, S. Ikegawa, S. Sakurai, S. Kihara, T.L. Maurissen, M. Nakamura, T. Matsumoto, H. Yoshitomi, M. Ikeya, N. Kawakami, T. Yamamoto, K. Woltjen, M. Ebisuya, J. Toguchida, and C. Alev. Recapitulating the human segmentation clock with pluripotent stem cells. Nature. 2020b;580(7801):124-129. PubMed PMID: 32238941.
  • Matsubara, K., A. Iwata, Y. Kawasaki, Y. Honda, and T. Yasumi. Incomplete Presentation of WHIM Syndrome: The Diagnostic Role of Dysmorphic Neutrophils in Bone Marrow. J Pediatr Hematol Oncol. 2020;42(7):449-450. PubMed PMID: 32769560.
  • Maekawa, H., S. Kawai, M. Nishio, S. Nagata, Y. Jin, H. Yoshitomi, S. Matsuda, and J. Toguchida. Prophylactic treatment of rapamycin ameliorates naturally developing and episode -induced heterotopic ossification in mice expressing human mutant ACVR1. Orphanet J Rare Dis. 2020;15(1):122. PubMed PMID: 32448372; PMCID: 7245788.
  • Katsuo, K., T. Honda, Y. Kaku, M. Nishitani-Isa, Y. Honda, T. Yasumi, and K. Kabashima. Pyoderma gangrenosum associated with chronic recurrent multifocal osteomyelitis as a possible paradoxical reaction to anti-tumor necrosis factor-α therapy. J Dermatol. 2020;47(8):e283-e284. PubMed PMID: 32515066.
  • Hamatani, M., H. Yamashita, H. Ochi, S. Ashida, Y. Hashi, Y. Okada, C. Fujii, K. Kawamura, R. Kitazawa, M. Nakagawa, T. Mizuno, R. Takahashi, and T. Kondo. Altered features of monocytes in adult onset leukoencephalopathy with axonal spheroids and pigmented glia: A clue to the pathomechanism of microglial dyshomeostasis. Neurobiology of disease. 2020;140:104867. PubMed PMID: 32276111.
2019~2016
  • Yoshitomi, H. Regulation of Immune Responses and Chronic Inflammation by Fibroblast-Like Synoviocytes. Front Immunol. 2019;10:1395. PubMed PMID: 31275325; PMCID: 6593115.
  • Wu, H., A. Witzl, and H. Ueno. Assessment of TCR signal strength of antigen-specific memory CD8(+) T cells in human blood. Blood Adv. 2019;3(14):2153-2163. PubMed PMID: 31320320; PMCID: PMC6650739.
  • Ueno, H. Tfh cell response in influenza vaccines in humans: what is visible and what is invisible. Curr Opin Immunol. 2019;59:9-14. PubMed PMID: 30921542.
  • Matsuda, M., Y. Yamanaka, M. Uemura, M. Osawa, M.K. Saito, A. Nagahashi, M. Nishio, L. Guo, S. Ikegawa, and S. Sakurai. Modeling the human segmentation clock with pluripotent stem cells. BioRxiv. 2019:562447.
  • Kawai, S., H. Yoshitomi, J. Sunaga, C. Alev, S. Nagata, M. Nishio, M. Hada, Y. Koyama, M. Uemura, K. Sekiguchi, H. Maekawa, M. Ikeya, S. Tamaki, Y. Jin, Y. Harada, K. Fukiage, T. Adachi, S. Matsuda, and J. Toguchida. In vitro bone-like nodules generated from patient-derived iPSCs recapitulate pathological bone phenotypes. Nat Biomed Eng. 2019;3(7):558-570. PubMed PMID: 31182836.
  • Caielli, S., D.T. Veiga, P. Balasubramanian, S. Athale, B. Domic, E. Murat, R. Banchereau, Z. Xu, M. Chandra, C.H. Chung, L. Walters, J. Baisch, T. Wright, M. Punaro, L. Nassi, K. Stewart, J. Fuller, D. Ucar, H. Ueno, J. Zhou, J. Banchereau, and V. Pascual. A CD4(+) T cell population expanded in lupus blood provides B cell help through interleukin-10 and succinate. Nat Med. 2019;25(1):75-81. PubMed PMID: 30478422; PMCID: PMC6325012.
  • Boisson, B., Y. Honda, M. Ajiro, J. Bustamante, M. Bendavid, A.R. Gennery, Y. Kawasaki, J. Ichishima, M. Osawa, H. Nihira, T. Shiba, T. Tanaka, M. Chrabieh, B. Bigio, H. Hur, Y. Itan, Y. Liang, S. Okada, K. Izawa, R. Nishikomori, O. Ohara, T. Heike, L. Abel, A. Puel, M.K. Saito, J.L. Casanova, M. Hagiwara, and T. Yasumi. Rescue of recurrent deep intronic mutation underlying cell type-dependent quantitative NEMO deficiency. J Clin Invest. 2019;129(2):583-597. PubMed PMID: 30422821; PMCID: PMC6355244.
  • Azukizawa, M., H. Ito, Y. Hamamoto, T. Fujii, Y. Morita, A. Okahata, T. Tomizawa, M. Furu, K. Nishitani, S. Kuriyama, S. Nakamura, H. Yoshitomi, T. Nakatani, T. Tsuboyama, M. Hamaguchi, S. Matsuda, and T. Yasuda. The Effects of Well-Rounded Exercise Program on Systemic Biomarkers Related to Cartilage Metabolism. Cartilage. 2019;10(4):451-458. PubMed PMID: 29644876; PMCID: 6755879.
  • Yoshitomi, H., S. Kobayashi, A. Miyagawa-Hayashino, A. Okahata, K. Doi, K. Nishitani, K. Murata, H. Ito, T. Tsuruyama, H. Haga, S. Matsuda, and J. Toguchida. Human Sox4 facilitates the development of CXCL13-producing helper T cells in inflammatory environments. Nat Commun. 2018;9(1):3762. PubMed PMID: 30232328; PMCID: 6145936.
  • Uzzan, M., M. Tokuyama, A.K. Rosenstein, C. Tomescu, I.N. SahBandar, H.M. Ko, L. Leyre, A. Chokola, E. Kaplan-Lewis, G. Rodriguez, A. Seki, M.J. Corley, J. Aberg, A. La Porte, E.Y. Park, H. Ueno, I. Oikonomou, I. Doron, I.D. Iliev, B.K. Chen, J. Lui, T.W. Schacker, G.C. Furtado, S.A. Lira, J.F. Colombel, A. Horowitz, J.K. Lim, N. Chomont, A.H. Rahman, L.J. Montaner, L.C. Ndhlovu, and S. Mehandru. Anti-alpha4beta7 therapy targets lymphoid aggregates in the gastrointestinal tract of HIV-1-infected individuals. Science translational medicine. 2018;10(461). PubMed PMID: 30282696; PMCID: PMC6314200.
  • Ueno, H. Location, Location, Location. Immunity. 2018;49(2):197-199. PubMed PMID: 30134195.
  • Sakaue, S., J. Hirata, Y. Maeda, E. Kawakami, T. Nii, T. Kishikawa, K. Ishigaki, C. Terao, K. Suzuki, M. Akiyama, N. Suita, T. Masuda, K. Ogawa, K. Yamamoto, Y. Saeki, M. Matsushita, M. Yoshimura, H. Matsuoka, K. Ikari, A. Taniguchi, H. Yamanaka, H. Kawaji, T. Lassmann, M. Itoh, H. Yoshitomi, H. Ito, K. Ohmura, R.F. AR, Y. Hayashizaki, P. Carninci, A. Kumanogoh, Y. Kamatani, M. de Hoon, K. Yamamoto, and Y. Okada. Integration of genetics and miRNA-target gene network identified disease biology implicated in tissue specificity. Nucleic Acids Res. 2018;46(22):11898-11909. PubMed PMID: 30407537; PMCID: PMC6294505.
  • Okada, Y., H. Ochi, C. Fujii, Y. Hashi, M. Hamatani, S. Ashida, K. Kawamura, H. Kusaka, S. Matsumoto, M. Nakagawa, T. Mizuno, R. Takahashi, and T. Kondo. Signaling via toll-like receptor 4 and CD40 in B cells plays a regulatory role in the pathogenesis of multiple sclerosis through interleukin-10 production. Journal of autoimmunity. 2018;88:103-113. PubMed PMID: 29146546.
  • Morita, Y., H. Ito, M. Ishikawa, T. Fujii, M. Furu, M. Azukizawa, A. Okahata, T. Tomizawa, S. Kuriyama, S. Nakamura, K. Nishitani, H. Yoshitomi, and S. Matsuda. Subchondral bone fragility with meniscal tear accelerates and parathyroid hormone decelerates articular cartilage degeneration in rat osteoarthritis model. J Orthop Res. 2018;36(7):1959-1968. PubMed PMID: 29251375.
  • Masamoto, K., B. Otsuki, S. Fujibayashi, K. Shima, H. Ito, M. Furu, M. Hashimoto, M. Tanaka, S. Lyman, H. Yoshitomi, S. Tanida, T. Mimori, and S. Matsuda. Factors influencing spinal sagittal balance, bone mineral density, and Oswestry Disability Index outcome measures in patients with rheumatoid arthritis. Eur Spine J. 2018;27(2):406-415. PubMed PMID: 29185111.
  • Ito, S., A. Endo, T. Okada, H. Yoshitomi, R. Hyakudomi, Y. Tajima, and K. Tanabe. A Case of Left Ventricular Thrombus with Superior Mesenteric Vein Thrombosis Due to Atopic Dermatitis. International Heart Journal. 2018;59(4):881-886. PubMed PMID: WOS:000440870400035.
  • Horiuchi, S., and H. Ueno. Potential Pathways Associated With Exaggerated T Follicular Helper Response in Human Autoimmune Diseases. Front Immunol. 2018;9:1630. PubMed PMID: 30061896; PMCID: PMC6054970.
  • Utsumi, T., S. Okada, K. Izawa, Y. Honda, G. Nishimura, R. Nishikomori, R. Okano, and M. Kobayashi. A Case with Spondyloenchondrodysplasia Treated with Growth Hormone. Front Endocrinol (Lausanne). 2017;8:157. PubMed PMID: 28740483; PMCID: PMC5502255.
  • Qu, K., L.C. Zaba, A.T. Satpathy, P.G. Giresi, R. Li, Y. Jin, R. Armstrong, C. Jin, N. Schmitt, Z. Rahbar, H. Ueno, W.J. Greenleaf, Y.H. Kim, and H.Y. Chang. Chromatin Accessibility Landscape of Cutaneous T Cell Lymphoma and Dynamic Response to HDAC Inhibitors. Cancer Cell. 2017;32(1):27-41 e24. PubMed PMID: 28625481; PMCID: PMC5559384.
  • Mori, M., M. Hashimoto, T. Matsuo, T. Fujii, M. Furu, H. Ito, H. Yoshitomi, J. Hirose, Y. Ito, S. Akizuki, R. Nakashima, Y. Imura, N. Yukawa, H. Yoshifuji, K. Ohmura, and T. Mimori. Cell-contact-dependent activation of CD4(+) T cells by adhesion molecules on synovial fibroblasts. Mod Rheumatol. 2017;27(3):448-456. PubMed PMID: 27623446.
  • Iwata, T., H. Ito, M. Furu, M. Ishikawa, M. Azukizawa, H. Yoshitomi, T. Fujii, H. Akiyama, and S. Matsuda. Subsidence of total ankle component associated with deterioration of an ankle scale in non-inflammatory arthritis but not in rheumatoid arthritis. Modern Rheumatology. 2017;27(3):417-424.
  • Ito, S., A. Endo, T. Okada, T. Nakamura, T. Sugamori, N. Takahashi, H. Yoshitomi, and K. Tanabe. Comparison of CTAC and prone imaging for the detection of coronary artery disease using CZT SPECT. Annals of Nuclear Medicine. 2017;31(8):629-635. PubMed PMID: WOS:000411969000009.
  • Fujii, T., E. Nishi, H. Ito, H. Yoshitomi, M. Furu, N. Okabe, M. Ohno, K. Nishi, Y. Morita, Y. Morita, M. Azukizawa, A. Okahata, T. Tomizawa, T. Kimura, and S. Matsuda. Nardilysin is involved in autoimmune arthritis via the regulation of tumour necrosis factor alpha secretion. Rmd Open. 2017;3(1):e000436. PubMed PMID: WOS:000443681800059.
  • Emori, T., J. Hirose, K. Ise, J.I. Yomoda, M. Kasahara, T. Shinkuma, H. Yoshitomi, H. Ito, M. Hashimoto, S. Sugahara, H. Fujita, N. Yamamoto, Y. Morita, S. Narumiya, and I. Aramori. Constitutive Activation of Integrin alpha9 Augments Self-Directed Hyperplastic and Proinflammatory Properties of Fibroblast-like Synoviocytes of Rheumatoid Arthritis. J Immunol. 2017;199(10):3427-3436. PubMed PMID: 29038247; PMCID: PMC5672818.
  • Ueno, H. Human Circulating T Follicular Helper Cell Subsets in Health and Disease. J Clin Immunol. 2016a. PubMed PMID: 26984851.
  • Ueno, H. T follicular helper cells in human autoimmunity. Curr Opin Immunol. 2016b;43:24-31. PubMed PMID: 27588918.
  • Schmitt, N., Y. Liu, S.E. Bentebibel, and H. Ueno. Molecular Mechanisms Regulating T Helper 1 versus T Follicular Helper Cell Differentiation in Humans. Cell Rep. 2016;16(4):1082-1095. PubMed PMID: 27425607.
  • Okada, T., A. Endo, S. Ito, T. Nakamura, T. Sugamori, N. Takahashi, H. Yoshitomi, and K. Tanabe. Acute Coronary Syndrome in a Puerperal Patient with Coronary Artery Ectasia due to a Coronary Artery Fistula. Internal Medicine. 2016;55(18):2635-2638. PubMed PMID: WOS:000384663200017.
  • Ogino, H., H. Ito, M. Furu, M. Ishikawa, H. Yoshitomi, and S. Matsuda. Limited extension after linked total elbow arthroplasty in patients with rheumatoid arthritis. Mod Rheumatol. 2016;26(3):347-351. PubMed PMID: 26344819.
  • Nishiguchi, S., H. Ito, M. Yamada, H. Yoshitomi, M. Furu, T. Ito, A. Shinohara, T. Ura, K. Okamoto, T. Aoyama, and T. Tsuboyama. Self-assessment of Rheumatoid Arthritis Disease Activity Using a Smartphone Application Development and 3-month Feasibility Study. Methods of Information in Medicine. 2016;55(1):65-69. PubMed PMID: WOS:000367827600009.
  • Nakashimai, H., F. Miyake, S. Ohki, S. Hattori, T. Matsubayashi, K. Izawa, R. Nishikomori, T. Heike, Y. Honda, and Y. Shigematsu. 2016. Febrile attacks triggered by milk allergy in an infant with mevalonate kinase deficiency. In Rheumatol Int. 1477-1478.
  • Mensa-Vilaro, A., M. Teresa Bosque, G. Magri, Y. Honda, H. Martínez-Banaclocha, M. Casorran-Berges, J. Sintes, E. González-Roca, E. Ruiz-Ortiz, T. Heike, J.J. Martínez-Garcia, A. Baroja-Mazo, A. Cerutti, R. Nishikomori, J. Yagüe, P. Pelegrín, C. Delgado-Beltran, and J.I. Aróstegui. Brief Report: Late-Onset Cryopyrin-Associated Periodic Syndrome Due to Myeloid-Restricted Somatic NLRP3 Mosaicism. Arthritis Rheumatol. 2016;68(12):3035-3041. PubMed PMID: 27273849.
  • Kobayashi, S., T. Watanabe, R. Suzuki, M. Furu, H. Ito, J. Ito, S. Matsuda, and H. Yoshitomi. TGF-beta induces the differentiation of human CXCL13-producing CD4(+) T cells. Eur J Immunol. 2016;46(2):360-371. PubMed PMID: 26541894; PMCID: PMC5063156.
  • Kathania, M., P. Khare, M. Zeng, B. Cantarel, H. Zhang, H. Ueno, and K. Venuprasad. Itch inhibits IL-17-mediated colon inflammation and tumorigenesis by ROR-gammat ubiquitination. Nature immunology. 2016;17(8):997-1004. PubMed PMID: 27322655.
  • Iwasaki, S., K. Motokura, Y. Honda, M. Mikami, D. Hata, and A. Hata. Vaccine-strain herpes zoster found in the trigeminal nerve area in a healthy child: A case report. J Clin Virol. 2016;85:44-47. PubMed PMID: 27835757.
  • Hamatani, Y., M. Iguchi, M. Nakamura, R. Ohtani, Y. Yamashita, D. Takagi, T. Unoki, M. Ishii, N. Masunaga, H. Ogawa, M. Hamatani, M. Abe, and M. Akao. Incidence and predictors of ischemic stroke during hospitalization for congestive heart failure. Heart and vessels. 2016a;31(7):1154-1161. PubMed PMID: 26219729.
  • Hamatani, M., N. Jingami, K. Uemura, N. Nakasone, H. Kinoshita, H. Yamakado, H. Ninomiya, and R. Takahashi. A case of variant biochemical phenotype of Niemann-Pick disease type C accompanying savant syndrome. Rinsho shinkeigaku = Clinical neurology. 2016b;56(6):424-429. PubMed PMID: 27181747.
  • Hamatani, M., N. Jingami, Y. Tsurusaki, S. Shimada, K. Shimojima, M. Asada-Utsugi, K. Yoshinaga, N. Uemura, H. Yamashita, K. Uemura, R. Takahashi, N. Matsumoto, and T. Yamamoto. The first Japanese case of leukodystrophy with ovarian failure arising from novel compound heterozygous AARS2 mutations. Journal of human genetics. 2016c;61(10):899-902. PubMed PMID: 27251004.
  • Gensous, N., N. Schmitt, C. Richez, H. Ueno, and P. Blanco. T follicular helper cells, interleukin-21 and systemic lupus erythematosus. Rheumatology (Oxford). 2016. PubMed PMID: 27498357.
  • Blanco, P., H. Ueno*, and N. Schmitt. T follicular helper (Tfh) cells in lupus: Activation and involvement in SLE pathogenesis. Eur J Immunol. 2016;46(2):281-290. PubMed PMID: 26614103.
  • Bentebibel, S.E., S. Khurana, N. Schmitt, P. Kurup, C. Mueller, G. Obermoser, A.K. Palucka, R.A. Albrecht, A. Garcia-Sastre, H. Golding, and H. Ueno. ICOS(+)PD-1(+)CXCR3(+) T follicular helper cells contribute to the generation of high-avidity antibodies following influenza vaccination. Sci Rep. 2016;6:26494. PubMed PMID: 27231124; PMCID: PMC4882544.
2015~2010
  • Ueno, H., and P. Blanco. OX40/OX40L axis: not a friend in autoimmunity. Oncotarget. 2015;6(26):21779-21780. PubMed PMID: 26314852.
  • Ueno, H., J. Banchereau, and C.G. Vinuesa. Pathophysiology of T follicular helper cells in humans and mice. Nature immunology. 2015;16(2):142-152. PubMed PMID: 25594465.
  • Shibuya, H., H. Yoshitomi, K. Murata, S. Kobayashi, M. Furu, M. Ishikawa, T. Fujii, H. Ito, and S. Matsuda. TNFalpha, PDGF, and TGFbeta synergistically induce synovial lining hyperplasia via inducible PI3Kdelta. Mod Rheumatol. 2015;25(1):72-78. PubMed PMID: 24716596.
  • Schmitt, N., and H. Ueno. Regulation of human helper T cell subset differentiation by cytokines. Curr Opin Immunol. 2015;34:130-136. PubMed PMID: 25879814; PMCID: 4465198.
  • Ogino, H., H. Ito, M. Furu, M. Ishikawa, H. Yoshitomi, and S. Matsuda. Outcome of shortened extra-small ulnar component in linked total elbow arthroplasty for patients with rheumatoid arthritis. Mod Rheumatol. 2015;25(6):849-853. PubMed PMID: 25800637.
  • Nakamura, S., H. Ito, H. Yoshitomi, S. Kuriyama, R.D. Komistek, and S. Matsuda. Analysis of the Flexion Gap on In Vivo Knee Kinematics Using Fluoroscopy. J Arthroplasty. 2015;30(7):1237-1242. PubMed PMID: WOS:000356184300031.
  • Jacquemin, C., N. Schmitt, C. Contin-Bordes, Y. Liu, P. Narayanan, J. Seneschal, T. Maurouard, D. Dougall, E.S. Davizon, H. Dumortier, I. Douchet, L. Raffray, C. Richez, E. Lazaro, P. Duffau, M.E. Truchetet, L. Khoryati, P. Mercie, L. Couzi, P. Merville, T. Schaeverbeke, J.F. Viallard, J.L. Pellegrin, J.F. Moreau, S. Muller, S. Zurawski, R.L. Coffman, V. Pascual, H. Ueno*, and P. Blanco*. OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response. Immunity. 2015;42(6):1159-1170. PubMed PMID: 26070486.
  • Hashimoto, M., T. Yamazaki, M. Hamaguchi, T. Morimoto, M. Yamori, K. Asai, Y. Isobe, M. Furu, H. Ito, T. Fujii, C. Terao, M. Mori, T. Matsuo, H. Yoshitomi, K. Yamamoto, W. Yamamoto, K. Bessho, and T. Mimori. Periodontitis and Porphyromonas gingivalis in preclinical stage of arthritis patients. PLoS One. 2015;10(4):e0122121. PubMed PMID: 25849461; PMCID: 4388350.
  • Chujo, D., T.S. Nguyen, E. Foucat, D. Blankenship, J. Banchereau, G.T. Nepom, D. Chaussabel, and H. Ueno. Adult-onset Type 1 Diabetes Patients Display Decreased IGRP-specific Tr1 cells in blood. Clinical immunology. 2015:doi:10.1016/j.clim.2015.1008.1014. PubMed PMID: 26341315.
  • Chen, J., G. Zurawski, S. Zurawski, Z. Wang, K. Akagawa, S. Oh, H. Ueno, J. Fay, J. Banchereau, W. Song, and A.K. Palucka. A novel vaccine for mantle cell lymphoma based on targeting cyclin D1 to dendritic cells via CD40. Journal of hematology & oncology. 2015;8:35. PubMed PMID: 25888530; PMCID: 4424584.
  • Bentebibel, S.E., C. Jacquemin, N. Schmitt, and H. Ueno. Analysis of human blood memory T follicular helper subsets. Methods Mol Biol. 2015;1291:187-197. PubMed PMID: 25836312.
  • Shiheido, H., K. Kitagori, C. Sasaki, S. Kobayashi, T. Aoyama, K. Urata, T. Oku, Y. Hirayama, H. Yoshitomi, M. Hikida, H. Yoshifuji, T. Mimori, T. Watanabe, and J. Shimizu. Human T cells expressing BEND3 on their surface represent a novel subpopulation that preferentially produces IL-6 and IL-8. Immun Inflamm Dis. 2014;2(1):35-43. PubMed PMID: WOS:000218714000004.
  • Schmitt, N., Y. Liu, S.E. Bentebibel, I. Munagala, L. Bourdery, K. Venuprasad, J. Banchereau, and H. Ueno. The cytokine TGF-beta co-opts signaling via STAT3-STAT4 to promote the differentiation of human TFH cells. Nature immunology. 2014a;15(9):856-865. PubMed PMID: 25064073.
  • Schmitt, N., S.E. Bentebibel, and H. Ueno. Phenotype and functions of memory Tfh cells in human blood. Trends in immunology. 2014b;35(9):436-442. PubMed PMID: 24998903; PMCID: 4152409.
  • Nishiguchi, S., H. Ito, M. Yamada, H. Yoshitomi, M. Furu, T. Ito, A. Shinohara, T. Ura, K. Okamoto, and T. Aoyama. Self-Assessment Tool of Disease Activity of Rheumatoid Arthritis by Using a Smartphone Application. Telemedicine and E-Health. 2014;20(3):235-240. PubMed PMID: WOS:000332013500009.
  • Neo, M., H. Yoshitomi, M. Takemoto, and M. Izeki. The reinforcement of a C2 laminar screw by a C2 laminar hook as an anchor of occipito-C2 fusion. European Journal of Orthopaedic Surgery & Traumatology. 2014;24(4):635-639.
  • Murata, K., H. Yoshitomi, M. Furu, M. Ishikawa, H. Shibuya, H. Ito, and S. Matsuda. MicroRNA-451 down-regulates neutrophil chemotaxis via p38 MAPK. Arthritis Rheumatol. 2014a;66(3):549-559. PubMed PMID: 24574214.
  • Murata, K., H. Ito, H. Yoshitomi, K. Yamamoto, A. Fukuda, J. Yoshikawa, M. Furu, M. Ishikawa, H. Shibuya, and S. Matsuda. Inhibition of miR-92a enhances fracture healing via promoting angiogenesis in a model of stabilized fracture in young mice. J Bone Miner Res. 2014b;29(2):316-326. PubMed PMID: 23857760.
  • Ishikawa, M., H. Ito, T. Kitaori, K. Murata, H. Shibuya, M. Furu, H. Yoshitomi, T. Fujii, K. Yamamoto, and S. Matsuda. MCP/CCR2 Signaling Is Essential for Recruitment of Mesenchymal Progenitor Cells during the Early Phase of Fracture Healing. Plos One. 2014;9(8):e104954. PubMed PMID: WOS:000341302700054.
  • Furu, M., M. Hashimoto, H. Ito, T. Fujii, C. Terao, N. Yamakawa, H. Yoshitomi, H. Ogino, M. Ishikawa, S. Matsuda, and T. Mimori. Discordance and accordance between patient's and physician's assessments in rheumatoid arthritis. Scandinavian Journal of Rheumatology. 2014;43(4):291-295. PubMed PMID: WOS:000340461800006.
  • Terao, C., M. Hashimoto, K. Yamamoto, K. Murakami, K. Ohmura, R. Nakashima, N. Yamakawa, H. Yoshifuji, N. Yukawa, D. Kawabata, T. Usui, H. Yoshitomi, M. Furu, R. Yamada, F. Matsuda, H. Ito, T. Fujii, and T. Mimori. Three Groups in the 28 Joints for Rheumatoid Arthritis Synovitis - Analysis Using More than 17,000 Assessments in the KURAMA Database. PLoS One. 2013;8(3):e59341. PubMed PMID: WOS:000316252500081.
  • Schmitt, N., and H. Ueno. Blood Tfh cells come with colors. Immunity. 2013;39(4):629-630. PubMed PMID: 24138878; PMCID: 3996729.
  • Schmitt, N., J. Bustamante, L. Bourdery, S.E. Bentebibel, S. Boisson-Dupuis, F. Hamlin, M.V. Tran, D. Blankenship, V. Pascual, D.A. Savino, J. Banchereau, J.L. Casanova, and H. Ueno. IL-12 receptor beta1 deficiency alters in vivo T follicular helper cell response in humans. Blood. 2013;121(17):3375-3385. PubMed PMID: 23476048; PMCID: 3637013.
  • Obermoser, G., S. Presnell, K. Domico, H. Xu, Y. Wang, E. Anguiano, L. Thompson-Snipes, R. Ranganathan, B. Zeitner, A. Bjork, D. Anderson, C. Speake, E. Ruchaud, J. Skinner, L. Alsina, M. Sharma, H. Dutartre, A. Cepika, E. Israelsson, P. Nguyen, Q.A. Nguyen, A.C. Harrod, S.M. Zurawski, V. Pascual, H. Ueno, G.T. Nepom, C. Quinn, D. Blankenship, K. Palucka, J. Banchereau, and D. Chaussabel. Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines. Immunity. 2013;38(4):831-844. PubMed PMID: 23601689; PMCID: 3681204.
  • Murata, K., M. Furu, H. Yoshitomi, M. Ishikawa, H. Shibuya, M. Hashimoto, Y. Imura, T. Fujii, H. Ito, T. Mimori, and S. Matsuda. Comprehensive microRNA Analysis Identifies miR-24 and miR-125a-5p as Plasma Biomarkers for Rheumatoid Arthritis. Plos One. 2013;8(7):e69118. PubMed PMID: WOS:000324146200059.
  • Kobayashi, S., K. Murata, H. Shibuya, M. Morita, M. Ishikawa, M. Furu, H. Ito, J. Ito, S. Matsuda, T. Watanabe, and H. Yoshitomi. A Distinct Human CD4+T Cell Subset That Secretes CXCL13 in Rheumatoid Synovium. Arthritis and Rheumatism. 2013;65(12):3063-3072. PubMed PMID: WOS:000327692600010.
  • Izeki, M., M. Neo, H. Ito, K. Nagai, T. Ishizaki, T. Okamoto, S. Fujibayashi, M. Takemoto, H. Yoshitomi, T. Aoyama, and S. Matsuda. Reduction of atlantoaxial subluxation causes airway stenosis. Spine (Phila Pa 1976). 2013;38(9):E513-520. PubMed PMID: 23392412.
  • Chujo, D., E. Foucat, T.S. Nguyen, D. Chaussabel, J. Banchereau, and H. Ueno. ZnT8-Specific CD4(+) T Cells Display Distinct Cytokine Expression Profiles between Type 1 Diabetes Patients and Healthy Adults. PLoS One. 2013;8(2):e55595. PubMed PMID: 23390544; PMCID: 3563599.
  • Bentebibel, S.E., S. Lopez, G. Obermoser, N. Schmitt, C. Mueller, C. Harrod, E. Flano, A. Mejias, R.A. Albrecht, D. Blankenship, H. Xu, V. Pascual, J. Banchereau, A. Garcia-Sastre, A.K. Palucka, O. Ramilo, and H. Ueno. Induction of ICOS+CXCR3+CXCR5+ TH cells correlates with antibody responses to influenza vaccination. Science translational medicine. 2013;5(176):176ra132. PubMed PMID: 23486778; PMCID: 3621097.
  • Yamada, M., T. Aoyama, S. Mori, S. Nishiguchi, K. Okamoto, T. Ito, S. Muto, T. Ishihara, H. Yoshitomi, and H. Ito. Objective assessment of abnormal gait in patients with rheumatoid arthritis using a smartphone. Rheumatology International. 2012;32(12):3869-3874. PubMed PMID: WOS:000311515600024.
  • Nishiguchi, S., M. Yamada, K. Nagai, S. Mori, Y. Kajiwara, T. Sonoda, K. Yoshimura, H. Yoshitomi, H. Ito, K. Okamoto, T. Ito, S. Muto, T. Ishihara, and T. Aoyama. Reliability and validity of gait analysis by android-based smartphone. Telemed J E Health. 2012;18(4):292-296. PubMed PMID: 22400972.
  • Murata, K., T. Kitaori, S. Oishi, N. Watanabe, H. Yoshitomi, S. Tanida, M. Ishikawa, T. Kasahara, H. Shibuya, N. Fujii, T. Nagasawa, T. Nakamura, and H. Ito. Stromal cell-derived factor 1 regulates the actin organization of chondrocytes and chondrocyte hypertrophy. PLoS One. 2012;7(5):e37163. PubMed PMID: 22623989; PMCID: 3356379.
  • Ishikawa, M., H. Ito, M. Akiyoshi, N. Kume, H. Yoshitomi, H. Mitsuoka, S. Tanida, K. Murata, H. Shibuya, T. Kasahara, A. Kakino, Y. Fujita, T. Sawamura, T. Yasuda, and T. Nakamura. Lectin-like Oxidized Low-Density Lipoprotein Receptor 1 Signal Is a Potent Biomarker and Therapeutic Target for Human Rheumatoid Arthritis. Arthritis Rheum-Us. 2012;64(4):1024-1034. PubMed PMID: WOS:000302475500011.
  • Chujo, D., E. Foucat, M. Takita, T. Itoh, K. Sugimoto, M. Shimoda, K. Yagi, M. Yamagishi, Y. Tamura, L. Yu, B. Naziruddin, M.F. Levy, H. Ueno, and S. Matsumoto. Emergence of a broad repertoire of GAD65-specific T-cells in type 1 diabetes patients with graft dysfunction after allogeneic islet transplantation. Cell Transplant. 2012;21(12):2783-2795. PubMed PMID: 22963904.
  • Yoshitomi, H., M. Neo, H. Ito, M. Takemoto, Y. Masaki, and T. Nakamura. Doppler ultrasonography and computed tomography angiography demonstrate positional occlusion of vertebral artery associated with one-sided destruction of the atlantoaxial lateral mass caused by rheumatoid arthritis: a case report. Spine (Phila Pa 1976). 2011;36(22):E1493-1496. PubMed PMID: 21304427.
  • Ueno, H., E. Klechevsky, N. Schmitt, L. Ni, A.L. Flamar, S. Zurawski, G. Zurawski, K. Palucka, J. Banchereau, and S. Oh. Targeting human dendritic cell subsets for improved vaccines. Seminars in immunology. 2011a;23(1):21-27. PubMed PMID: 21277223; PMCID: 3071344.
  • Ueno, H., J. Fay, A.K. Palucka, and J. Banchereau. [Harnessing myeloid dendritic cell subsets in novel cancer immunotherapy]. [Rinsho ketsueki] The Japanese journal of clinical hematology. 2011b;52(7):505-513. PubMed PMID: 21821982.
  • Tanida, S., H. Yoshitomi, M. Ishikawa, T. Kasahara, K. Murata, H. Shibuya, H. Ito, and T. Nakamura. IL-27-producing CD14(+) cells infiltrate inflamed joints of rheumatoid arthritis and regulate inflammation and chemotactic migration. Cytokine. 2011;55(2):237-244. PubMed PMID: 21592822.
  • Palucka, K., H. Ueno, J. Fay, and J. Banchereau. Dendritic cells and immunity against cancer. J Intern Med. 2011a;269(1):64-73. PubMed PMID: 21158979.
  • Palucka, K., H. Ueno, and J. Banchereau. Recent developments in cancer vaccines. J Immunol. 2011b;186(3):1325-1331. PubMed PMID: 21248270.
  • Morita, R., N. Schmitt, S.E. Bentebibel, R. Ranganathan, L. Bourdery, G. Zurawski, E. Foucat, M. Dullaers, S. Oh, N. Sabzghabaei, E.M. Lavecchio, M. Punaro, V. Pascual, J. Banchereau, and H. Ueno. Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretion. Immunity. 2011;34(1):108-121. PubMed PMID: 21215658.
  • Bentebibel, S.E., N. Schmitt, J. Banchereau, and H. Ueno. Human tonsil B-cell lymphoma 6 (BCL6)-expressing CD4+ T-cell subset specialized for B-cell help outside germinal centers. Proc Natl Acad Sci U S A. 2011;108(33):E488-497. PubMed PMID: 21808017; PMCID: 3158181.
  • Ueno, H., N. Schmitt, A.K. Palucka, and J. Banchereau. Dendritic cells and humoral immunity in humans. Immunol Cell Biol. 2010a;88(4):376-380. PubMed PMID: 20309010; PMCID: PMC2865578.
  • Ueno, H., N. Schmitt, E. Klechevsky, A. Pedroza-Gonzalez, T. Matsui, G. Zurawski, S. Oh, J. Fay, V. Pascual, J. Banchereau, and K. Palucka. Harnessing human dendritic cell subsets for medicine. Immunol Rev. 2010b;234(1):199-212. PubMed PMID: 20193020; PMCID: PMC2847489.
  • Ueno, H., A.K. Palucka, and J. Banchereau. The expanding family of dendritic cell subsets. Nat Biotechnol. 2010c;28(8):813-815. PubMed PMID: 20697407.
  • Tanaka, S., S. Maeda, M. Hashimoto, C. Fujimori, Y. Ito, S. Teradaira, K. Hirota, H. Yoshitomi, T. Katakai, A. Shimizu, T. Nomura, N. Sakaguchi, and S. Sakaguchi. Graded attenuation of TCR signaling elicits distinct autoimmune diseases by altering thymic T cell selection and regulatory T cell function. J Immunol. 2010;185(4):2295-2305. PubMed PMID: 20644168.
  • Palucka, K., H. Ueno, G. Zurawski, J. Fay, and J. Banchereau. Building on dendritic cell subsets to improve cancer vaccines. Curr Opin Immunol. 2010a;22(2):258-263. PubMed PMID: 20226644; PMCID: PMC2854185.
  • Palucka, K., H. Ueno, L. Roberts, J. Fay, and J. Banchereau. Dendritic cells: are they clinically relevant? Cancer J. 2010b;16(4):318-324. PubMed PMID: 20693842; PMCID: 2919819.
  • Palucka, K., H. Ueno, L. Roberts, J. Fay, and J. Banchereau. Dendritic Cell Subsets as Vectors and Targets for Improved Cancer Therapy. Curr Top Microbiol Immunol. 2010c. PubMed PMID: 20490776; PMCID: 2944902.
  • Nishitani, K., H. Ito, T. Hiramitsu, R. Tsutsumi, S. Tanida, T. Kitaori, H. Yoshitomi, M. Kobayashi, and T. Nakamura. PGE2 inhibits MMP expression by suppressing MKK4-JNK MAP kinase-c-JUN pathway via EP4 in human articular chondrocytes. J Cell Biochem. 2010;109(2):425-433. PubMed PMID: 19998410.
  • Murata, K., H. Yoshitomi, S. Tanida, M. Ishikawa, K. Nishitani, H. Ito, and T. Nakamura. Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis. Arthritis Research & Therapy. 2010;12(3):1-14. PubMed PMID: WOS:000280227900031.
  • Hashimoto, M., K. Hirota, H. Yoshitomi, S. Maeda, S. Teradaira, S. Akizuki, P. Prieto-Martin, T. Nomura, N. Sakaguchi, J. Kohl, B. Heyman, M. Takahashi, T. Fujita, T. Mimori, and S. Sakaguchi. Complement drives Th17 cell differentiation and triggers autoimmune arthritis. J Exp Med. 2010;207(6):1135-1143. PubMed PMID: 20457757; PMCID: 2882841.
2009~
  • Yoshitomi, H., S. Shikata, H. Ito, T. Nakayama, and T. Nakamura. Manufacturers affect clinical results of THA with zirconia heads: a systematic review. Clin Orthop Relat Res. 2009;467(9):2349-2355. PubMed PMID: 19184615; PMCID: 2866928.
  • Tanida, S., H. Yoshitomi, K. Nishitani, M. Ishikawa, T. Kitaori, H. Ito, and T. Nakamura. CCL20 produced in the cytokine network of rheumatoid arthritis recruits CCR6+ mononuclear cells and enhances the production of IL-6. Cytokine. 2009;47(2):112-118. PubMed PMID: 19535263.
  • Schmitt, N., R. Morita, L. Bourdery, S.E. Bentebibel, S.M. Zurawski, J. Banchereau, and H. Ueno. Human dendritic cells induce the differentiation of interleukin-21-producing T follicular helper-like cells through interleukin-12. Immunity. 2009;31(1):158-169. PubMed PMID: 19592276; PMCID: PMC2731623.
  • Palucka, K., H. Ueno, J. Fay, and J. Banchereau. Harnessing dendritic cells to generate cancer vaccines. Ann N Y Acad Sci. 2009;1174:88-98. PubMed PMID: 19769741; PMCID: PMC2759270.
  • Noguchi, H., S. Matsumoto, N. Onaca, B. Naziruddin, A. Jackson, T. Ikemoto, M. Shimoda, Y. Fujita, D. Chujo, Y. Iwanaga, H. Nagata, T. Okitsu, N. Kobayashi, H. Ueno, D. Chaussabel, P. Grayburn, J. Banchereau, and M.F. Levy. Ductal injection of JNK inhibitors before pancreas preservation prevents islet apoptosis and improves islet graft function. Human gene therapy. 2009;20(1):73-85. PubMed PMID: 18925829.
  • Klechevsky, E., M. Liu, R. Morita, R. Banchereau, L. Thompson-Snipes, A.K. Palucka, H. Ueno, and J. Banchereau. Understanding human myeloid dendritic cell subsets for the rational design of novel vaccines. Hum Immunol. 2009;70(5):281-288. PubMed PMID: 19236899; PMCID: PMC2674516.
  • Kitaori, T., H. Ito, H. Yoshitomi, T. Aoyama, T. Fujii, T. Mimori, and T. Nakamura. Severe erosive arthropathy requiring surgical treatments in systemic lupus erythematosus. Mod Rheumatol. 2009a;19(4):431-436. PubMed PMID: 19365707.
  • Kitaori, T., H. Ito, E.A. Schwarz, R. Tsutsumi, H. Yoshitomi, S. Oishi, M. Nakano, N. Fujii, T. Nagasawa, and T. Nakamura. Stromal Cell-Derived Factor 1/CXCR4 Signaling Is Critical for the Recruitment of Mesenchymal Stem Cells to the Fracture Site During Skeletal Repair in a Mouse Model. Arthritis Rheum-Us. 2009b;60(3):813-823. PubMed PMID: WOS:000264211900022.
  • Ito, Y., T. Usui, S. Kobayashi, M. Iguchi‐Hashimoto, H. Ito, H. Yoshitomi, T. Nakamura, M. Shimizu, D. Kawabata, and N. Yukawa. Gamma/delta T cells are the predominant source of interleukin‐17 in affected joints in collagen‐induced arthritis, but not in rheumatoid arthritis. Arthritis & Rheumatism: Official Journal of the American College of Rheumatology. 2009a;60(8):2294-2303.
  • Ito, H., M. Neo, T. Sakamoto, S. Fujibayashi, H. Yoshitomi, and T. Nakamura. Subaxial subluxation after atlantoaxial transarticular screw fixation in rheumatoid patients. Eur Spine J. 2009b;18(6):869-876. PubMed PMID: 19337758; PMCID: 2899668.
  • Dullaers, M., D. Li, Y. Xue, L. Ni, I. Gayet, R. Morita, H. Ueno, K.A. Palucka, J. Banchereau, and S. Oh. A T cell-dependent mechanism for the induction of human mucosal homing immunoglobulin A-secreting plasmablasts. Immunity. 2009;30(1):120-129. PubMed PMID: 19144318; PMCID: PMC2659635.
  • Chaussabel, D., H. Ueno, J. Banchereau, and C. Quinn. Data management: it starts at the bench. Nature immunology. 2009;10(12):1225-1227. PubMed PMID: 19915619; PMCID: PMC2788787.
  • Banchereau, J., E. Klechevsky, N. Schmitt, R. Morita, K. Palucka, and H. Ueno. Harnessing human dendritic cell subsets to design novel vaccines. Ann N Y Acad Sci. 2009;1174:24-32. PubMed PMID: 19769733; PMCID: PMC2759267.
  • Wakasa-Morimoto, C., T. Toyosaki-Maeda, T. Matsutani, R. Yoshida, S. Nakamura-Kikuoka, M. Maeda-Tanimura, H. Yoshitomi, K. Hirota, M. Hashimoto, H. Masaki, Y. Fujii, T. Sakata, Y. Tsuruta, R. Suzuki, N. Sakaguchi, and S. Sakaguchi. Arthritis and pneumonitis produced by the same T cell clones from mice with spontaneous autoimmune arthritis. Int Immunol. 2008;20(10):1331-1342. PubMed PMID: 18711120.
  • Palucka, A.K., H. Ueno, J. Fay, and J. Banchereau. Dendritic cells: a critical player in cancer therapy? J Immunother. 2008;31(9):793-805. PubMed PMID: 18833008; PMCID: PMC2716088.
  • Klechevsky, E., R. Morita, M. Liu, Y. Cao, S. Coquery, L. Thompson-Snipes, F. Briere, D. Chaussabel, G. Zurawski, A.K. Palucka, Y. Reiter, J. Banchereau, and H. Ueno. Functional specializations of human epidermal Langerhans cells and CD14+ dermal dendritic cells. Immunity. 2008;29(3):497-510. PubMed PMID: 18789730; PMCID: PMC2688399.
  • Ito, H., M. Neo, S. Fujibayashi, M. Miyata, H. Yoshitomi, and T. Nakamura. Atlantoaxial transarticular screw fixation with posterior wiring using polyethylene cable - Facet fusion despite posterior graft resorption in rheumatoid patients. Spine. 2008;33(15):1655-1661. PubMed PMID: WOS:000257393600007.
  • Vence, L., A.K. Palucka, J.W. Fay, T. Ito, Y.J. Liu, J. Banchereau, and H. Ueno. Circulating tumor antigen-specific regulatory T cells in patients with metastatic melanoma. Proc Natl Acad Sci U S A. 2007;104(52):20884-20889. PubMed PMID: 18093940; PMCID: PMC2409236.
  • Ueno, H., E. Klechevsky, R. Morita, C. Aspord, T. Cao, T. Matsui, T. Di Pucchio, J. Connolly, J.W. Fay, V. Pascual, A.K. Palucka, and J. Banchereau. Dendritic cell subsets in health and disease. Immunol Rev. 2007a;219:118-142. PubMed PMID: 17850486.
  • Ueno, H., C.M. Hawrylowicz, and J. Banchereau. Immunological intervention in human diseases. J Transl Med. 2007b;5:59. PubMed PMID: 18036229; PMCID: PMC2176053.
  • Palucka, A.K., H. Ueno, J.W. Fay, and J. Banchereau. Taming cancer by inducing immunity via dendritic cells. Immunol Rev. 2007;220:129-150. PubMed PMID: 17979844.
  • Ito, H., M. Neo, M. Yoshida, S. Fujibayashi, H. Yoshitomi, and T. Nakamura. Efficacy of computer-assisted pedicle screw insertion for cervical instability in RA patients. Rheumatol Int. 2007a;27(6):567-574. PubMed PMID: 17094002.
  • Ito, H., T. Matsumoto, H. Yoshitomi, R. Kakinoki, and T. Nakamura. The outcome of peri-operative humeral condylar fractures after total elbow replacement in patients with rheumatoid arthritis. J Bone Joint Surg Br. 2007b;89(1):62-65. PubMed PMID: 17259418.
  • Hirota, K., H. Yoshitomi, M. Hashimoto, S. Maeda, S. Teradaira, N. Sugimoto, T. Yamaguchi, T. Nomura, H. Ito, T. Nakamura, N. Sakaguchi, and S. Sakaguchi. Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. J Exp Med. 2007a;204(12):2803-2812. PubMed PMID: 18025126; PMCID: 2118525.
  • Hirota, K., M. Hashimoto, H. Yoshitomi, S. Tanaka, T. Nomura, T. Yamaguchi, Y. Iwakura, N. Sakaguchi, and S. Sakaguchi. T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17(+) Th cells that cause autoimmune arthritis. Journal of Experimental Medicine. 2007b;204(1):41-47. PubMed PMID: WOS:000243753600008.
  • Cao, T.*, H. Ueno*, C. Glaser, J.W. Fay, A.K. Palucka, and J. Banchereau. Both Langerhans cells and interstitial DC cross-present melanoma antigens and efficiently activate antigen-specific CTL. Eur J Immunol. 2007;37(9):2657-2667. PubMed PMID: 17683111.
  • Sakaguchi, S., T. Takahashi, H. Hata, H. Yoshitomi, S. Tanaka, K. Hirota, T. Nomura, and N. Sakaguchi. 2006. SKG mice, a monogenic model of autoimmune arthritis due to altered signal transduction in T-cells. In The Hereditary Basis of Rheumatic Diseases. Springer, 147-159.
  • Palucka, A.K.*, H. Ueno*, J. Connolly, F. Kerneis-Norvell, J.P. Blanck, D.A. Johnston, J. Fay, and J. Banchereau. Dendritic cells loaded with killed allogeneic melanoma cells can induce objective clinical responses and MART-1 specific CD8+ T-cell immunity. J Immunother. 2006;29(5):545-557. PubMed PMID: 16971810.
  • Fay, J.W., A.K. Palucka, S. Paczesny, M. Dhodapkar, D.A. Johnston, S. Burkeholder, H. Ueno, and J. Banchereau. Long-term outcomes in patients with metastatic melanoma vaccinated with melanoma peptide-pulsed CD34(+) progenitor-derived dendritic cells. Cancer Immunol Immunother. 2006;55(10):1209-1218. PubMed PMID: 16331519.
  • Yoshitomi, H., and S. Sakaguchi. [Aetiology of rheumatoid arthritis]. Nihon Rinsho. 2005a;63(9):1517-1521. PubMed PMID: 16164205.
  • Yoshitomi, H., and S. Sakaguchi. SKG mice as a model of RA. Nihon rinsho. Japanese journal of clinical medicine. 2005b;63:40-45.
  • Yoshitomi, H., N. Sakaguchi, K. Kobayashi, G.D. Brown, T. Tagami, T. Sakihama, K. Hirota, S. Tanaka, T. Nomura, and I. Miki. A role for fungal β-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice. The Journal of experimental medicine. 2005;201(6):949-960.
  • Palucka, A.K., M.V. Dhodapkar, S. Paczesny, H. Ueno, J. Fay, and J. Banchereau. Boosting vaccinations with peptide-pulsed CD34+ progenitor-derived dendritic cells can expand long-lived melanoma peptide-specific CD8+ T cells in patients with metastatic melanoma. J Immunother. 2005a;28(2):158-168. PubMed PMID: 15725960.
  • Palucka, A.K., J. Connolly, H. Ueno, J. Kohl, S. Paczesny, M. Dhodapkar, J. Fay, and J. Banchereau. Spontaneous proliferation and type 2 cytokine secretion by CD4+T cells in patients with metastatic melanoma vaccinated with antigen-pulsed dendritic cells. J Clin Immunol. 2005b;25(3):288-295. PubMed PMID: 15981095.
  • Dubsky, P., H. Ueno, B. Piqueras, J. Connolly, J. Banchereau, and A.K. Palucka. Human dendritic cell subsets for vaccination. J Clin Immunol. 2005;25(6):551-572. PubMed PMID: 16380819.
  • Banchereau, J., H. Ueno, M. Dhodapkar, J. Connolly, J.P. Finholt, E. Klechevsky, J.P. Blanck, D.A. Johnston, A.K. Palucka, and J. Fay. Immune and clinical outcomes in patients with stage IV melanoma vaccinated with peptide-pulsed dendritic cells derived from CD34+ progenitors and activated with type I interferon. J Immunother. 2005;28(5):505-516. PubMed PMID: 16113607.
  • Ueno, H., I. Tcherepanova, O. Reygrobellet, E. Laughner, C. Ventura, A.K. Palucka, and J. Banchereau. Dendritic cell subsets generated from CD34+ hematopoietic progenitors can be transfected with mRNA and induce antigen-specific cytotoxic T cell responses. J Immunol Methods. 2004;285(2):171-180. PubMed PMID: 14980432.
  • Hata, H., N. Sakaguchi, H. Yoshitomi, Y. Iwakura, K. Sekikawa, Y. Azuma, C. Kanai, E. Moriizumi, T. Nomura, T. Nakamura, and S. Sakaguchi. Distinct contribution of IL-6, TNF-alpha, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice. J Clin Invest. 2004;114(4):582-588. PubMed PMID: 15314695; PMCID: PMC503774.
  • Banchereau, J., J. Fay, S. Paczesny, H. Ueno, M. Dhodapkarz, and A.K. Palucka. Dendritic cells as melanoma vaccines. Development of Therapeutic Cancer Vaccines. . 2004;116:147-156. PubMed PMID: 15603190.
  • Palucka, A.K., J. Gatlin, J.P. Blanck, M.W. Melkus, S. Clayton, H. Ueno, E.T. Kraus, P. Cravens, L. Bennett, A. Padgett-Thomas, F. Marches, M. Islas-Ohlmayer, J.V. Garcia, and J. Banchereau. Human dendritic cell subsets in NOD/SCID mice engrafted with CD34+ hematopoietic progenitors. Blood. 2003;102(9):3302-3310. PubMed PMID: 12869510.
  • Paczesny, S., H. Ueno, J. Fay, J. Banchereau, and A.K. Palucka. Dendritic cells as vectors for immunotherapy of cancer. Semin Cancer Biol. 2003;13(6):439-447. PubMed PMID: 15001163.
  • Ueno, H., K. Katamura, H. Hattori, Y. Yamaguchi, and T. Nakahata. Acute lethal encephalopathy in systemic juvenile rheumatoid arthritis. Pediatr Neurol. 2002;26(4):315-317. PubMed PMID: 11992763.
  • Fujibayashi, S., J. Shikata, H. Yoshitomi, C. Tanaka, K. Nakamura, and T. Nakamura. Bilateral phrenic nerve palsy as a complication of anterior decompression and fusion for cervical ossification of the posterior longitudinal ligament. Spine. 2001;26(12):e281-e286.
  • Ariga, T., N. Oda, I. Sanstisteban, F.X. Arredondo-Vega, M. Shioda, H. Ueno, K. Terada, K. Kobayashi, M.S. Hershfield, and Y. Sakiyama. Molecular basis for paradoxical carriers of adenosine deaminase (ADA) deficiency that show extremely low levels of ADA activity in peripheral blood cells without immunodeficiency. J Immunol. 2001;166(3):1698-1702. PubMed PMID: 11160213.
  • Ueno, H., S. Matsuda, K. Katamura, M. Mayumi, and S. Koyasu. ZAP-70 is required for calcium mobilization but is dispensable for mitogen-activated protein kinase (MAPK) superfamily activation induced via CD2 in human T cells. Eur J Immunol. 2000;30(1):78-86. PubMed PMID: 10602029.
  • Katamura, K., T. Fukui, T. Kiyomasu, K. Ohmura, J. Iio, and H. Ueno. Regulation of CD31 expression and interleukin-4 production by human cord blood CD4+ T cells with interleukin-4 and interleukin-7. Pediatr Int. 2000;42(2):126-133. PubMed PMID: 10804726.
  • Ueno, H., K. Katamura, T. Yorifuji, K. Ohmori, T. Kiyomasu, J. Iio, K. Ohmura, and M. Mayumi. Further characterization of memory T cells existing in a case of CD8 deficiency. Hum Immunol. 1999;60(11):1049-1053. PubMed PMID: 10600001.
  • Matsuda, S., T. Suzuki-Fujimoto, A. Minowa, H. Ueno, K. Katamura, and S. Koyasu. Temperature-sensitive ZAP70 mutants degrading through a proteasome-independent pathway. Restoration of a kinase domain mutant by Cdc37. J Biol Chem. 1999;274(49):34515-34518. PubMed PMID: 10574909.
  • Kiyomasu, T., K. Katamura, H. Ueno, J. Iio, K. Ohmura, T. Heike, and K. Furusho. Hypomethylation of the proximal and intronic regulatory regions of the IFN-gamma gene is not essential for its transcription by naive CD4+ T cells cultured with IL-4. Immunol Lett. 1999;69(2):239-245. PubMed PMID: 10482358.
  • Katamura, K., T. Fukui, T. Kiyomasu, J. Iio, G. Tai, H. Ueno, T. Heike, M. Mayumi, and K. Furusho. IL-4 and prostaglandin E2 inhibit hypomethylation of the 5' regulatory region of IFN-gamma gene during differentiation of naive CD4+ T cells. Mol Immunol. 1998;35(1):39-45. PubMed PMID: 9683262.
  • Fukui, T., K. Katamura, N. Abe, T. Kiyomasu, J. Iio, H. Ueno, M. Mayumi, and K. Furusho. IL-7 induces proliferation, variable cytokine-producing ability and IL-2 responsiveness in naive CD4+ T-cells from human cord blood. Immunol Lett. 1997;59(1):21-28. PubMed PMID: 9334853.
  • Abe, N., K. Katamura, N. Shintaku, T. Fukui, T. Kiyomasu, J. Iio, H. Ueno, G. Tai, M. Mayumi, and K. Furusho. Prostaglandin E2 and IL-4 provide naive CD4+ T cells with distinct inhibitory signals for the priming of IFN-gamma production. Cell Immunol. 1997;181(1):86-92. PubMed PMID: 9344500.
  • Kubota, M., Y. Hoshino, H. Doi, H. Ueno, Y. Nishida, H. Hirota, and Y. Akiyama. Myelodysplastic syndrome with t(9;11)(p22;q23) after treatment for B-cell acute lymphoblastic leukemia without epipodophyllotoxins. Acta haematologica. 1994;92(1):33-35. PubMed PMID: 7985479.
  • Yoshitomi, H., S. Abo, N. Yamashita, K. Ikeda, M. Takeda, and S. Goto. [Plasma protein-furosemide binding in acute renal failure in rabbits]. Yakugaku Zasshi. 1983;103(5):589-593. PubMed PMID: 6644550.